The Major Personality Trait Linked To Depression Risk

The Major Personality Trait Linked To Depression Risk post image

Among the major personality
traits, it shows the strongest link to depression.

Negative emotionality is
linked to a higher risk of depression, data from millions of people finds.
Negative emotionality, or
being neurotic, involves a tendency towards fear and worry.
People who are neurotic are
more likely to experience negative emotions like fear, jealousy, guilt, worry
and envy.
The good news is that a
depressive personality can be changed, contrary to what many people think.
The study’s conclusions come
from analysing data from over two million people.
Their DNA revealed 269 genes
related to depression.
Certain genes were also
related to some lifestyle choice, like smoking.
The study shows that
experiencing depression is linked to personality, which is partly controlled by
Raliza Stoyanova, of Wellcome, who funded the study, said:
“This large study is an
important advance in understanding how genetic variability might contribute to
risk for depression. Given that current treatments work for only half of those
who need them, the study provides some intriguing clues for future research to
follow up — for example that biological pathways involved in developing the
condition may not be the same as those involved in responding to treatment.”
Sophie Dix, Director of Research at mental health charity MQ, said:
“This study adds to the weight
of evidence that genes are one of the key risk factors in depression, which is
also impacted by life events such as social environment and trauma. The value
of this could really be seen when looking into the development of personalised
treatments — a welcome step given the dearth of innovation in identifying new
approaches. We have seen very little advancement in nearly 50 years for people
living with depression and right now the avenues available are not working for
The study was published in the
journal Nature Neuroscience (Howard et al., 2019).
Kayode Ojo
Kayode Emmanuel Ojo is the Co-Founder and Managing Director at SHEFFA Limited. He is presently studying Computer Science at the National Open University, Victoria Island, Lagos.